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KMID : 0828620070110010001
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Journal of Korean Arthroscopy Society
2007 Volume.11 No. 1 p.1 ~ p.6
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Second Look Arthroscopic Finding after Fibrin Matrix Autologous Chondrocyte Implantation for the Treatment of Articular Cartilage Defect of the Knee - Preliminary Report -
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Choi Sung-Wook
Park Sun-Won
Oh In-Suk
Kim Myung-Ku
Kim Ryuh-Sup
Lee Jong-Min
Lee Moon
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Abstract
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Purpose:The purpose of this preliminary report is to investigate the short term outcome of performing gel type fibrin matrix autologous chondrocyte implantation to patients who have damaged knee joint cartilage using secondary arthroscopy.
Materials and Method :Six patients who have damaged knee joint cartilage were involved. The average size of defect was 5.13 cm2. While performing primary arthroscopy, whole layer of cartilage bone was obtained either from the margin of damaged cartilage or the bilateral margin of a trochlea. The cartilaginous cells were obtained for culture for four to six weeks. While performing secondary minimal invasive arthrotomy, gel type fibrin matrix autologous chondrocyte was implanted on the chondral defect site.
Results:4 among 6 patients to be more than good in Modified Cincinnati Knee Scoring system. Lysholm function score was 59.5 preoperatively, and it improved to 76.25. ICRS grading by performing secondary arthroscopy revealed 4 out of 6 patients to be nearly normal.
Conclusions:Gel type fibrin matrix autologous chondrocyte implantation is a treatment for cartilage defect, which takes less time to operate than the conventional implantation. In addition, this method minimizes the size of incision and allows arthroscopic surgery. However, long term follow up and more case study is thought to be necessary.
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KEYWORD
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Chondral defect, Autologous chondrocyte implantation
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